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Good Positive and Negative Likelihood Ratios

Diabetic Ketoacidosis: Likelihood Ratios

Introduction: Acidemia from ketone production in a state of (at least functional) hypoinsulinemia and hyperglycemia. Much more common in type 1 Diabetes Mellitus.

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Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Hyperglycemia and suspicious symptoms 14% patients presenting to the ED; glucose > 200 and either known diabetic + DKA-like symptoms or no diabetes diagnosis

Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090

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The likelihood ratios of findings for Diabetic Ketoacidosis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Good Positive and Negative Likelihood Ratios
FindingResult +LR-LR
[ + ] Urine Ketones + 0 - 3.20
[ + ] Anion Gap + 0 - 6.10.1
[ + ] Abnormal Serum Bicarbonate + 0 - 840.2