Diabetic Ketoacidosis: Likelihood Ratios

Introduction: Acidemia from ketone production in a state of (at least functional) hypoinsulinemia and hyperglycemia. Much more common in type 1 Diabetes Mellitus.

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Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
Hyperglycemia and suspicious symptoms	14%	patients presenting to the ED; glucose > 200 and either known diabetic + DKA-like symptoms or no diabetes diagnosis Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090
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The likelihood ratios of findings for Diabetic Ketoacidosis are listed below. See the left navigation bar to change the display.

Finding	+LR	-LR	Comments, Study
Urine Ketones	3.2	0	urine dipstick Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090
Anion Gap	6.1	0.1	Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090
Abnormal Serum Bicarbonate	84	0.2	HCO3 < 15 mEq/l Study: Ann Emerg Med. 1999 Sep;34(3):342-6. PMID: 10459090