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Good Positive and Negative Likelihood Ratios

Coronary Artery Disease: Likelihood Ratios

Introduction: See UpToDate page http://www.utdol.com/online/content/topic.do?topicKey=chd/59850 for good prevalence data and discussion. "Investigators from Duke confirmed that age, gender, and chest pain symptoms were the most powerful predictors of CHD, but showed that other characteristics also increase the probability of CHD. These included diabetes mellitus, which was the strongest predictor, smoking, hypercholesterolemia, and Q waves or ST-T changes on the resting ECG."

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Tags: Cardiac Problem Vascular Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Rate of CAD by age, gender, and type of chest pain 0% http://www.utdol.com/online/content/topic.do?topicKey=chd/59850

(combined data from Diamond, GA, Forrester, JS, N Engl J Med 1979; 300:1350; and from Weiner, DA, Ryan, TJ, McCabe, CH, et al, N Engl J Med 1979; 301:230.)

Men with typical angina 89% http://www.utdol.com/online/content/topic.do?topicKey=chd/59850

(from the Coronary Artery Surgery Study)

Women with typical angina 63% http://www.utdol.com/online/content/topic.do?topicKey=chd/59850

(from the Coronary Artery Surgery Study)

More, Edit...

The likelihood ratios of findings for Coronary Artery Disease are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Good Positive and Negative Likelihood Ratios
FindingResult +LR-LR
[ + ] Cardiac CT + 0 - 7.70
[ + ] PET/CT scan + 0 - 5.10.1
[ + ] Nuclear Perfusion + 0 - 3.80.2
[ + ] Cardiac MRI + 0 - 2.90.2
[ + ] Cardiac CT + 0 - 26.70.2
[ + ] Stress Echocardiography + 0 - 6.30.3
[ + ] Nuclear Perfusion + 0 - 2.90.3
[ + ] Exercise ECG + 0 - 30.4