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Good Positive and Negative Likelihood Ratios

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Congenital Heart Disease: Likelihood Ratios

Introduction: None written.

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Tags: Cardiac Problem Congenital Tag this Diagnosis.

Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
Infants	1.1%	J Pediatr. 2008 Jun;152(6):761-5. PMID: 18492511
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The likelihood ratios of findings for Congenital Heart Disease are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Good Positive and Negative Likelihood Ratios
Finding	Result	+LR	-LR
[ + ] Pulse Oximetry on First Day of Life	+ 0 -	128.5	0.2
this is for diagnosis of critical CHDs most missed are left sided obstructions along with clinical exam, sensitivity rises to 88.6% Study: J Pediatr. 2008 Jun;152(6):761-5. PMID: 18492511

Poorly Diagnostic Findings
Finding	Result	+LR	-LR
[ + ] Routine Exam at Six Weeks		Sensitivity = 65%
specificity not assessed Study: Arch Dis Child Fetal Neonatal Ed. 1999 Jan;80(1):F49-53. PMID: 10325813
[ + ] Routine Neonatal Exam		Sensitivity = 45%
specificity not assessed even with abnormal exam, only about a third were directly referred to cardiology Study: Arch Dis Child Fetal Neonatal Ed. 1999 Jan;80(1):F49-53. PMID: 10325813
[ + ] Symptomatic or Other Congenital Abnormalities		Sensitivity = 33%
specificity not assessed Study: Arch Dis Child Fetal Neonatal Ed. 1999 Jan;80(1):F49-53. PMID: 10325813