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Sensitive and Specific Findings

Cleft Lip: Sensitivity and Specificity

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The sensitivity and specificity of findings for Cleft Lip are listed below. See the left navigation bar to change the display.

Sensitive and Specific Findings

Finding SensitivitySpecificity Comments, Study
MRI, prenatal Edit 100%100%

In a study of 34 pregnant women, 29 of which had a facial cleft, the MRI correctly identified all anomalies without error. In addition, MRI outperformed prenatal ultrasound.

Study: Ultrasound Obstet Gynecol. 2010 Oct;36(4):445-51.

What does magnetic resonance imaging add to the prenatal ultrasound diagnosis of facial clefts?

Mailáth-Pokorny M, Worda C, Krampl-Bettelheim E, Watzinger F, Brugger PC, Prayer D.

Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.

PMID: 20617504

Ultrasound, prenatal: Absence of muscle fibers crossing the lip Edit 95%92%

The ultrasonographer must specifically look at a frontal view to make the diagnosis

Study: Ultrasound Obstet Gynecol. 2010 Nov;36(5):596-600. doi: 10.1002/uog.7739.

Detection of lip, alveolar ridge and hard palate abnormalities using two-dimensional ultrasound enhanced with the three-dimensional reverse-face view.

Sommerlad M, Patel N, Vijayalakshmi B, Morris P, Hall P, Ahmad T, Campbell S, Lees C.

Cleft Net East, Addenbrookes Hospital, Cambridge, UK.

PMID 20617510