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Sensitive and Specific Findings

Specific Findings

Cervical Cancer: Sensitivity and Specificity

Introduction: Screening tests center on finding atypical cells or cervical intraepithelial neoplasia (up to squamous carcinoma in situ). The tests listed here are generally for finding atypia and/or CIN. The pathogenesis of cervical cancer is always or almost always from HPV infection.

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Tags: Gynecologic Neoplasm Tag this Diagnosis.

The sensitivity and specificity of findings for Cervical Cancer are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %. Post-Test Probability (Predictive Value): %. Switch to display mode.
**Note that calculating probabilities from more than one finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)
Sensitive and Specific Findings
FindingResult SensitivitySpecificity
[ + ] HPV DNA PCR + 0 - 94.6%94.1%
[ + ] Pap Smear Plus HPV PCR + 0 - 100%92.5%
Specific Findings
FindingResult SensitivitySpecificity
[ + ] ThinPrep Pap Smear + 0 - 76%86%
[ + ] Traditional Pap Smear + 0 - 30%86%