Cardiac Amyloidosis: Sensitivity and Specificity
Introduction: Amyloidosis represents abnormal deposition of amyloid fibrils within the soft tissues. It can affect various organs, including the heart where it deposits in the myocardium. Clinical features are those of diastolic Congestive Heart Failure.
Note that the diagnosis of systemic amyloidosis can be obtained by biopsy of other involved organs (though this does not necessarily prove cardiac involvement, which has a worse prognosis).