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Sensitive and Specific Findings

Specific Findings

Atopic Dermatitis: Sensitivity and Specificity

Introduction: aka Eczema

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Tags: Autoimmune Tag this Diagnosis.

The sensitivity and specificity of findings for Atopic Dermatitis are listed below. See the left navigation bar to change the display.

Pre-Test Probability (Prevalence): %.	Post-Test Probability (Predictive Value): %.	Switch to display mode.
Note that calculating probabilities from more than one** finding is inherently inaccurate because findings are not independent. (For example, using two positive findings that share a common pathogenesis is likely to overestimate the true probability.)

Sensitive and Specific Findings
Finding	Result	Sensitivity	Specificity
[ + ] Schultz-Larsen criteria	+ 0 -	91%	87%
>= 50 points Study: Br J Dermatol. 2008 Apr;158(4):754-65. PMID: 18241277
[ + ] Hanifin and Rajka Criteria	+ 0 -	92%	86%
3 major + 3 minor Study: Br J Dermatol. 2008 Apr;158(4):754-65. PMID: 18241277

Specific Findings
Finding	Result	Sensitivity	Specificity
[ + ] UK Criteria	+ 0 -	10%	94%
[sensitivity ranged from 10-100% in studies] Pruritus + 3 minor: 1. Onset below age 2* 2. History of flexural involvement 3. History of a generally dry skin 4. Personal history of other atopic disease** 5. visible flexural dermatitis as per photographic protocol not used in children under 4 years * in children aged under 4 years,history of atopic disease in a first degree relative may be included Study: Br J Dermatol. 2008 Apr;158(4):754-65. PMID: 18241277