Angioedema: Sensitivity and Specificity

Introduction: None written.

Prevalence

Patients on Enalapril

0.68%

Incidence and characteristics of angioedema associated with enalapril.

Kostis JB, Kim HJ, Rusnak J, Casale T, Kaplan A, Corren J, Levy

Arch Intern Med. 2005;165(14):1637.

PMID16043683

The sensitivity and specificity of findings for Angioedema are listed below. See the left navigation bar to change the display.

Findings With Unspecified Accuracy

Finding	Sensitivity	Specificity	Comments, Study
Hoarseness	No accuracy specified.		Study: no study specified.
Throat tightness	No accuracy specified.		Study: no study specified.
Swallowing difficulty	No accuracy specified.		Study: no study specified.
Edema, non pitting	No accuracy specified.		Airway edema: face, lips, larynx Other: bowels Study: no study specified.
Expsure to allergen	No accuracy specified.		Mast cell-mediated angioedema triggered by exposure to allergen: Begins minutes after exposure to allergen, peaks after a few hours and resolves arter 24-48 hours Associated symptoms of allergic reaction include PRURITIS, BRONCHOSPASM, THROAT TIGHTNESS and HYPOTENSION Study: no study specified.
Exposure to Bradykinin	No accuracy specified.		- Seen with angiotensin converting enzyme (ACE) inhibitor use Not associated with urticaria, bronchospasm, or other allergic symptoms Study: no study specified.
Colicky Pain	No accuracy specified.		- Seen in patients on ACE inhibitors and with C1 inhibitory deficiency (hereditary or acquired) Study: no study specified.