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Findings With Unspecified Accuracy

Angioedema: Sensitivity and Specificity

Introduction: None written.

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Population / CalculatorPrevalence Comments / Study / Link
Patients on Enalapril 0.68% Incidence and characteristics of angioedema associated with enalapril.

Kostis JB, Kim HJ, Rusnak J, Casale T, Kaplan A, Corren J, Levy

Arch Intern Med. 2005;165(14):1637.


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The sensitivity and specificity of findings for Angioedema are listed below. See the left navigation bar to change the display.

Findings With Unspecified Accuracy

Finding SensitivitySpecificity Comments, Study
Hoarseness Edit No accuracy specified.

Study: no study specified.

Throat tightness Edit No accuracy specified.

Study: no study specified.

Swallowing difficulty Edit No accuracy specified.

Study: no study specified.

Edema, non pitting Edit No accuracy specified.

Airway edema: face, lips, larynx

Other: bowels

Study: no study specified.

Expsure to allergen Edit No accuracy specified.

Mast cell-mediated angioedema triggered by exposure to allergen:

  • Begins minutes after exposure to allergen, peaks after a few hours and resolves arter 24-48 hours
  • Associated symptoms of allergic reaction include PRURITIS, BRONCHOSPASM, THROAT TIGHTNESS and HYPOTENSION
  • Study: no study specified.

    Exposure to Bradykinin Edit No accuracy specified.

    - Seen with angiotensin converting enzyme (ACE) inhibitor use

  • Not associated with urticaria, bronchospasm, or other allergic symptoms
  • Study: no study specified.

    Colicky Pain Edit No accuracy specified.

    - Seen in patients on ACE inhibitors and with C1 inhibitory deficiency (hereditary or acquired)

    Study: no study specified.