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Good Positive and Negative Likelihood Ratios

Good Positive Likelihood Ratio

Anaphylaxis: Likelihood Ratios

Introduction: None written.

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Tags: Autoimmune Tag this Diagnosis.

The likelihood ratios of findings for Anaphylaxis are listed below. See the left navigation bar to change the display.

Good Positive and Negative Likelihood Ratios

Finding +LR-LR Comments, Study
Serum Tryptase
Duplicate Edit
12.20.1

tryptase > 8.23 ng/ml (cutoff of 13 ng/ml decreased sensitivity to 35% without increasing specificity)

patients with a clinical allergic rxn < 6 hr in duration - anaphylaxis versus angioedema or urticaria

Study: Allergy. 1999 Jun;54(6):602-6. PMID: 10435474

Serial Serum Tryptase Edit 36.50.3

increase > 2 mcg/l from 15 min to 60 min post exposure

Study: Emerg Med Australas. 2004 Apr;16(2):120-4. PMID: 15239726

Serum Tryptase
Duplicate Edit
7.90.5

peak tryptase > 9 mcg/l (15 min and 60 min timepoints)

Study: Emerg Med Australas. 2004 Apr;16(2):120-4. PMID: 15239726

Good Positive Likelihood Ratio

Finding +LR-LR Comments, Study
Serum Tryptase
Duplicate Edit
5.10.7

peak tryptase > 12 mcg/l (15 and 60 min timepoints)

Study: Emerg Med Australas. 2004 Apr;16(2):120-4. PMID: 15239726