Adrenal Insufficiency: Sensitivity and Specificity
Introduction: If primary (i.e. due to lack of production by the adrenals), it is known as Addison's Disease.
Gold standard tests include the metyrapone test (for secondary AI - looking for an increase in ACTH after metyrapone blocks cortisol synthesis) and the cortisol response to insulin-induced hypoglycemia.
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The sensitivity and specificity of findings for Adrenal Insufficiency are listed below. See the left navigation bar to change the display.