Acute Streptococcal Pharyngitis: Likelihood Ratios

Introduction: None written.

Differential Diagnoses include: Kawasaki Disease, Viral Pharyngitis

The likelihood ratios of findings for Acute Streptococcal Pharyngitis are listed below. See the left navigation bar to change the display.

Good Positive and Negative Likelihood Ratios

Finding	+LR	-LR	Comments, Study
Throat Culture	inf	0	Study: JAMA. 2004 Apr 7;291(13):1587-95. PMID: 15069046
Rapid Streptococcal Antigen Test Duplicate	8.3	0.1	Study: no study specified.
Rapid Streptococcal Antigen Test Duplicate	83	0.2	Study: JAMA. 2004 Apr 7;291(13):1587-95. PMID: 15069046
Modified Centor Criteria	10.6	0.2	=>2 criteria: history of objective fever (>38C) exudative pharyngitis lack of cough tender cervical LAD +1 for <=15 years old, -1 for >45 years old Differential Diagnosis: Viral Pharyngitis Study: CMAJ. 2000 Oct 3;163(7):811-5. PMID: 11033707 rather similar results also in JAMA. 2004 Apr 7;291(13):1587-95. PMID: 15069046
Physical Exam	3.1	0.4	all 4: Tender Adenopathy, Pharyngeal Exudates, Pharyngeal Erythema, and Enlarged Tonsils Study: Acad Emerg Med. 2000 Oct;7(10):1104-9. PMID: 11015241

Good Positive Likelihood Ratio

2.9

0.9

>100.5F

Study: Acad Emerg Med. 2000 Oct;7(10):1104-9. PMID: 11015241

Poorly Diagnostic Findings

Finding	+LR	-LR	Comments, Study
Centor Criteria Duplicate	1.5	0.9	=4 criteria: subjective or objective fever (>38C) exudative pharyngitis lack of cough tender cervical LAD Study: Br J Gen Pract. 2005 Aug;55(517):615-9. PMID: 16105370
Centor Criteria Duplicate	1.4	0.9	=3 criteria: subjective or objective fever (>38C) exudative pharyngitis lack of cough tender cervical LAD Study: Br J Gen Pract. 2005 Aug;55(517):615-9. PMID: 16105370
Centor Criteria Duplicate	1.5	0.8	>=3 criteria: subjective or objective fever (>38C) exudative pharyngitis lack of cough tender cervical LAD Study: Br J Gen Pract. 2005 Aug;55(517):615-9. PMID: 16105370