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Poorly Diagnostic Findings

Findings With Unspecified Accuracy

Acoustic neuroma: Likelihood Ratios

Introduction: None written.

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Tags: Neoplasm Otolaryngology Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
Overall 0.02% This is based on a retrospective analysis of 46,000 MRI done for other reasons, which identified 8 acoustic neuromas.

The prevalence of "incidental" acoustic neuroma.

Lin D; Hegarty JL; Fischbein NJ; Jackler RK

Arch Otolaryngol Head Neck Surg 2005 Mar;131(3):241-4.

Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, USA.

PMID 15781765

Neurofibromatosis Type 2 100% Eventually, close to 100% of NF Type 2 patients will develop bilateral acoustic neuromas.

Neurologist. 2006 Mar;12(2):86-93.

Neurofibromatosis types 1 and 2.

Yohay K.

Division of Child Neurology and Pediatrics, Johns Hopkins University, Baltimore,

Maryland 21287, USA. kyohay@jhmi.edu

PMID: 16534445

More, Edit...

The likelihood ratios of findings for Acoustic neuroma are listed below. See the left navigation bar to change the display.

Poorly Diagnostic Findings

Finding +LR-LR Comments, Study
Hearing loss, asymmetric Edit Sensitivity = 95%

In this study, 5% of patients with an acoustic neuroma had normal or symmetric hearing. Abnormal hearing was defined as an interaural difference of > or =15 dB at a single frequency or > or =10 dB at two or more frequencies, and an interaural speech reception threshold difference of > or =20 dB, or a speech discrimination score of > or =20%

Study: Am J Otol. 1998 Mar;19(2):212-8.

Acoustic neuromas presenting with normal or symmetrical hearing: factors

associated with diagnosis and outcome.

Lustig LR, Rifkin S, Jackler RK, Pitts LH.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University,

Baltimore, Maryland, USA.

PMID 9520059

Auditory Brainstem Response test (ABR) Edit Sensitivity = 85%

Abnormal ABR, measured by CN V latency

This test can be helpful both in diagnosing acoustic neuromas and also in identifying such tumors that are amenable to resection with salvage of hearing

Note: In the following study based on 51 patients with acoustic neuromas the sensitivity was higher for extracranial tumors (24/25 = 96%) than for intracranial tumors (10/15) = 67%

Study: The sensitivity of auditory brainstem response testing in small acoustic neuromas.

Wilson DF; Hodgson RS; Gustafson MF; Hogue S; Mills L

Laryngoscope 1992 Sep;102(9):961-4.

Portland Ear Medical Group, Ore. 97209.

PMID 1518359

Findings With Unspecified Accuracy

Finding +LR-LR Comments, Study
MRI with Gadolinium Contrast Edit No accuracy specified.

MRI with gadolinium with milimeter sections through the internal auditory meatus can be used to detect tumors as small as 1 to 2 mm in diameter

Study: no study specified.

Vertigo Edit No accuracy specified.

Study: no study specified.

Cranial Nerve V abnormalities Edit No accuracy specified.

facial hypoesthesia or paresthesia

Study: no study specified.

Cranial Nerve VII abnormalities Edit No accuracy specified.

Includes:

  • Facial nerve motor weakness as measured by House-Brackman Scale
  • Loss of sensation in posterior superior aspect of external ear canal
  • Study: no study specified.

    Headache Edit No accuracy specified.

    Study: no study specified.