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Pelvic Inflammatory Disease: Sensitivity and Specificity

Introduction: Infection of the internal female genital organs.

50% from Chlamydia trachomatis. Others: Neisseria gonorrheae, mycoplasma, etc.

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Tags: Infection Tag this Diagnosis.

The sensitivity and specificity of findings for Pelvic Inflammatory Disease are listed below. See the left navigation bar to change the display.

Sensitive and Specific Findings

Finding SensitivitySpecificity Comments, Study
Abdominal MRI Edit 95%93%

note: small series

Study: J Infect. 2000 Jan;40(1):31-41. PMID: 10762109

Nuclear WBC Scan Edit 95%85%

Study: J Infect. 2000 Jan;40(1):31-41. PMID: 10762109

Specific Findings

Finding SensitivitySpecificity Comments, Study
Purulent endocervical secretion Edit 23%93%

in 61 women with non-specific lower abdominal pain.

Study: Infect Dis Obstet Gynecol. 2002;10(4):171-80; PMID: 12648310

Proctitis Symptoms Edit 10%92%

Study: Sex Transm Infect. 2003 Dec;79(6):491-4. PMID: 14663128

Rebound Edit 25%90%

in 61 women with non-specific lower abdominal pain.

Study:

Infect Dis Obstet Gynecol. 2002;10(4):171-80; PMID: 12648310

Emesis Edit 14%88%

Study: Sex Transm Infect. 2003 Dec;79(6):491-4. PMID: 14663128

Sensitive Findings

Finding SensitivitySpecificity Comments, Study
Adnexal tenderness Edit 93%6%

in 61 women with non-specific lower abdominal pain

Study: Infect Dis Obstet Gynecol. 2002;10(4):171-80; PMID: 12648310

Transvaginal US Edit 87%50%

NOTE: very large CI for specificity (5-100%)!

Study: J Infect. 2000 Jan;40(1):31-41. PMID: 10762109

Negative Findings

Finding SensitivitySpecificity Comments, Study
Leukocytosis Edit 50%40%

Study: J Infect. 2000 Jan;40(1):31-41. PMID: 10762109

Adnexal tenderness Edit 93%6%

in 61 women with non-specific lower abdominal pain

Study: Infect Dis Obstet Gynecol. 2002;10(4):171-80; PMID: 12648310

Poorly Diagnostic Findings

Finding SensitivitySpecificity Comments, Study
Vaginal Bleeding Edit 25%77%

Study: Sex Transm Infect. 2003 Dec;79(6):491-4. PMID: 14663128

Vaginal discharge Edit 40%73%

in 61 women with non-specific lower abdominal pain.

Another meta-analysis gave 74%/24%.

Study: Infect Dis Obstet Gynecol. 2002;10(4):171-80; PMID: 12648310

Sex Transm Infect. 2003 Dec;79(6):491-4. PMID: 14663128

Adnexal Mass Edit 52%70%

palpable

Study: Sex Transm Infect. 2003 Dec;79(6):491-4. PMID: 14663128

hearing loss Edit 47%64%

Study: Sex Transm Infect. 2003 Dec;79(6):491-4. PMID: 14663128

Menstrual Irregularity Edit 45%57%

Study: Sex Transm Infect. 2003 Dec;79(6):491-4. PMID: 14663128

Elevated ESR Edit 80%50%

Study: J Infect. 2000 Jan;40(1):31-41. PMID: 10762109

Cervical motion tenderness Edit 63%40%

in 61 women with non-specific lower abdominal pain

Study: Infect Dis Obstet Gynecol. 2002;10(4):171-80; PMID: 12648310

Abdominal US Edit Sensitivity = 78%

Study: J Infect. 2000 Jan;40(1):31-41. PMID: 10762109