Irritable Bowel Syndrome: Likelihood Ratios

Introduction: None written.

Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
General population	5%	by Rome I criteria Aliment Pharmacol Ther. 2004 Aug 1;20(3):339-45. PMID 15274671
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The likelihood ratios of findings for Irritable Bowel Syndrome are listed below. See the left navigation bar to change the display.

Good Positive and Negative Likelihood Ratios

Finding	+LR	-LR	Comments, Study
Kruis Scoring System	7	0.3	>=44 points Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Manning Criteria	2.8	0.3	>=3: Abdominal pain relieved by defecation More frequent stools at onset of pain Looser stools with onset of pain Passage of mucus per rectum Feeling of incomplete evacuation Patient-reported visible abdominal distension Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Rome I Criteria	4.7	0.3	Abdominal pain or discomfort relieved with defecation or associated with a change in stool frequency or consistency (>= 3 months), plus >= 2 of the following on at least 25% of occasions: Altered stool frequency Altered stool form Altered stool passage Passage of mucus per rectum Bloating or distension Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793

Good Negative Likelihood Ratio

1.3

0.3

Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793

Good Positive Likelihood Ratio

2.1

0.6

Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793

Poorly Diagnostic Findings

Finding	+LR	-LR	Comments, Study
Patient-reported abdominal distension	1.7	0.8	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
More frequent stools at onset of pain	1.9	0.7	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Pain relieved by defecation	1.8	0.6	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Mucus per rectum	1.2	0.9	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793
Feeling of incomplete evacuation	1.3	0.6	Study: JAMA. 2008;300(15):1793-1805. http://jama.ama-assn.org/cgi/content/full/300/15/1793