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Poorly Diagnostic Findings

Eclampsia: Sensitivity and Specificity

Introduction: Eclampsia is defined by seizures in pregnancy. Usually patients first develop pre-eclampsia, defined by hypertension and proteinuria. Treatment of pre-eclamptic patients with magnesium helps prevent eclampsia (and also, magnesium is the most effective treatment of eclamptic seizures).

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Tags: Obstetrical Tag this Diagnosis.

Prevalence

Population / CalculatorPrevalence Comments / Study / Link
All Pregnancies 0.00049% BMJ 1994 Nov 26;309(6966):1395-400. PMID 7819845
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The sensitivity and specificity of findings for Eclampsia are listed below. See the left navigation bar to change the display.

Poorly Diagnostic Findings

Finding SensitivitySpecificity Comments, Study
Uric Acid Edit 75.7%64%

serum uric acid >= 350mmol/l

Study: BJOG. 2006 Apr;113(4):369-78. PMID: 16553648

Proteinuria Edit Sensitivity = 81%

Study: Am J Obstet Gynecol 1990 Sep;163(3):1049-54 PMID 2403130

Hypertension Edit Sensitivity = 79%

diastolic > 90mmHg

Study: Am J Obstet Gynecol 1990 Sep;163(3):1049-54 PMID 2403130

Edema Edit Sensitivity = 68%

Study: Am J Obstet Gynecol 1990 Sep;163(3):1049-54 PMID 2403130

Headache, Vision Disturbance, or Epigastric Pain Edit Sensitivity = 59%

(antecedent)

Study: BMJ 1994 Nov 26;309(6966):1395-400. PMID 7819845

Proteinuria and Hypertension Edit Sensitivity = 57%

so 57% had proteinuria+HTN at the last antenatal visit. Similarly, of those that had seizures in the hospital, only 62% had proteinuria+HTN when they arrived at the hospital initially.

Study: BMJ 1994 Nov 26;309(6966):1395-400. PMID 7819845

Headache Edit Sensitivity = 50%

(antecedent)

Study: BMJ 1994 Nov 26;309(6966):1395-400. PMID 7819845

Visual Disturbances Edit Sensitivity = 19%

(antecedent)

Study: BMJ 1994 Nov 26;309(6966):1395-400. PMID 7819845

Epigastric Pain Edit Sensitivity = 19%

(antecedent)

Study: BMJ 1994 Nov 26;309(6966):1395-400. PMID 7819845

Headache, Vision Disturbance, and Epigastric Pain Edit Sensitivity = 4%

(antecedent)

Study: BMJ 1994 Nov 26;309(6966):1395-400. PMID 7819845