Ectopic Pregnancy: Sensitivity and Specificity

Introduction: See Pregnancy for beta-hCG diagnostic test accuracies.

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Prevalence

Population / Calculator	Prevalence	Comments / Study / Link
Pregnancies	2%	http://www.utdol.com/online/content/topic.do?topicKey=gen_gyne/6639
Women presenting to ED with first trimester bleeding, pain, or both	12%	6-16% http://www.utdol.com/online/content/topic.do?topicKey=gen_gyne/6639
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The sensitivity and specificity of findings for Ectopic Pregnancy are listed below. See the left navigation bar to change the display.

Specific Findings

Finding	Sensitivity	Specificity	Comments, Study
Trans-Vaginal Ultrasound	74%	100%	spec = 99.9%. Diagnostic criteria included sonographic evidence of an empty intrauterine cavity and adnexal mass and/or extrauterine gestational sac. For all patients where the diagnosis was "pregnancy of unknown location", ectopic pregnancy was later confirmed Study: Hum Reprod. 2007 Nov;22(11):2824-8. PMID 17855406
Adnexal Mass	9%	96%	Study: Crochet, J. R., Bastian, L. A., & Chireau, M. V. (2013). Does This Woman Have an Ectopic Pregnancy? JAMA, 309(16), 1722. doi:10.1001/jama.2013.3914
Cervical motion tenderness	45%	91%	Study: Crochet, J. R., Bastian, L. A., & Chireau, M. V. (2013). Does This Woman Have an Ectopic Pregnancy? JAMA, 309(16), 1722. doi:10.1001/jama.2013.3914

Poorly Diagnostic Findings

Adnexal tenderness

61%

65%

Study: Crochet, J. R., Bastian, L. A., & Chireau, M. V. (2013). Does This Woman Have an Ectopic Pregnancy? JAMA, 309(16), 1722. doi:10.1001/jama.2013.3914